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The glucagon receptor (GCGR) is activated by glucagon a hormone produced by pancreatic alpha cells that raises blood glucose and drives hepatic energy mobilisation

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US patent 2276508, Nabenhauer FP, "Method for the separation of optically active alpha-methylphenethylamine", published 17 March 1942, assigned to Smith Kline French 1 2 "Approved Treatments for Attention Deficit Hyperactivity Disorder: Amphetamine (Adderall), Methylphenidate (Ritalin), and Atomoxetine (Straterra)"