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Currently, the three leading options prescribed specifically for weight loss are: Semaglutide (Ozempic/Wegovy) Average weight loss: 14 to 16% of body weight FDA-approved for chronic weight management Tirzepatide (Zepbound) Average weight loss: 20 to 22% of body weight FDA-approved for chronic weight management A dual GLP-1/GIP receptor agonist that has shown superior weight loss results compared to semaglutide alone roughly 20% body weight reduction vs

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Weeks 8 through 12: New normal By this point, your body has largely adapted

But within 12 months of stopping treatment, they regained two-thirds of the weight they had lost, along with a significant reversal of improvements in some cardiometabolic markers, such as those related to diabetes and heart disease

Nazarzadeh M, Bidel Z, Canoy D, Copland E, Bennett DA, Dehghan A, et al