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Similar content being viewed by others Introduction Drug-induced liver injury have now gradually become the leading causes of acute liver failure in developed countries and acetaminophen (APAP) abuse is the predominant cause of drug-induced hepatotoxicity with associated acute liver failure (Fisher and Curry 2019

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Significantly, the Procleave protease cleavage prediction server (procleave.erc.monash.edu.au) (13) identified the GPX1 active site octameric sequence ASLU/GTTV as a highly ranked possible cleavage site for a cathepsin S-like cysteine protease (Figure 2G)

OS-related molecular markers ROS are core initiators of OS in cells

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