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They contain the same active ingredient semaglutide, tirzepatide or orforglipron but add minor but clinically important modifications such as using a different salt form, adding different inactive ingredients and varying drug concentrations or dosages

Earlier studies, including those published in JAMA Psychiatry, have shown similar signals with reduced alcohol consumption and less craving in people treated with semaglutide

Cardiovascular disease and myocardial abnormalities in nonalcoholic fatty liver disease