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Higher water volumes reduce concentration but require a larger draw
High-dose oral therapy (10002000 micrograms daily) can be effective even in pernicious anaemia, as approximately 1% of B12 is absorbed through passive diffusion independent of intrinsic factor
Its affordable, easy, and convenient
While direct cortisol measurements were not specifically reported in the published safety trials, the comprehensive metabolic monitoring across 900+ participants showed no clinically significant hormonal changes, and the mechanism of action provides no pathway for cortisol stimulation
The upper arm will be cleaned and prepared and a small needle will be used to administer the B12 intramuscularly
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