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Another study by Chearskul et al
Muscle cramps during GLP-1 therapy are typically caused by indirect factors including electrolyte depletion (especially magnesium and potassium) from gastrointestinal side effects, dehydration from reduced fluid intake or vomiting/diarrhea, rapid weight loss with some lean mass reduction, and increased physical activity exceeding current conditioning levels
However, these results are usually limited to skin health improvements, such as reduced pigmentation and increased brightness, rather than systemic effects
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He points to a clinical trial published in The New England Journal of Medicine studying the impact of semaglutide in people who were diagnosed with both overweight or obesity and heart disease, but who had no history of diabetes
GSH and GSSG levels were measured as previously described (21)
