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Those with naturally high NNMT activity might respond more dramatically to inhibition, while those with lower baseline activity might see more modest effects
PubMed: 19324939 Angiogenic Effects of AOD 9604 in Tissue-Engineered Cartilage Constructs in vitro Huang AH, Motlekar NA, Stein A, et al
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Low levels often cause fatigue and weakness
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