fatigue with tirzepatide and - What to Know (2026) fatigue after tirzepatide shot Feeling

Your care team will explore all available options with you

With Wegovy, you might experience bloating, nausea and vomiting, constipation or diarrhea, headache, and fatigue, Maselli says (13)

Healthcare providers can assess whether symptoms represent expected medication effects, require symptomatic management, warrant dose adjustment, or indicate an unrelated condition requiring specific treatment

Restall IJ, Cseh O, Richards LM, Pugh TJ, Luchman HA, Weiss S

In the future, you might receive a gut microbiome analysis that identifies exactly which GLP-1-supporting strains you are deficient in, followed by a personalized probiotic formulation targeting your specific gaps