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The existence of Na + -dependent GSH transporters at the luminal endothelial cell membranes of these organs are most likely the mechanism for these organs ability to conduct uphill transport of GSH from low plasma GSH concentration (~1020 M) to high GSH endothelial cellular concentration (mM) (Fig

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Research has demonstrated that Dihexa binds to HGF with remarkably high affinity (Kd = 65 picomolar) and acts as an allosteric modulator, potentiating HGF activity even at subthreshold concentrations