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Although there is a dearth of bioavailability data for many of the peptide nasal sprays, a study showed that direct intratracheal instillation of a lyophilized powder at high concentrations could achieve reasonable levels of systemic absorption [13]
One of these compounds, PMP, received an FDA approval for treatment of epilepsy, which acts on both AMPARs and KARs (Taniguchi et al., 2022
10.3389/fnins.2020.00213 Front
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