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Research has investigated its role in sleep regulation, stress response, neuroendocrine modulation, and its potential interaction with delta-wave sleep activity in the CNS

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A 2014 gene expression analysis by Pickart, Vasquez-Soltero, and Margolina found that GHK-Cu modulated 4,048 human genes at a concentration of just 1 micromolar, with a net "restorative" signature shifting expression patterns toward profiles associated with younger tissue [4]

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