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To interrogate the mechanisms underlying NRF2-directed regulation of this core gene set, we compared mean promoter (1 kb restricted) ChIP-seq signal in A549 for NRF2, p300, as well as the histone marks H3K4me3 and H3K27ac, which are enriched at promoters and enhancers, respectively

gut inflammation and immune regulation

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Family physicians can assist patients in setting weight loss goals, improving nutrition, increasing physical activity, addressing barriers to change, and developing strategies to maintain long-term lifestyle changes