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Clinical trials have demonstrated substantial weight loss with semaglutide therapy, often in the range of 515% of body weight
The difference between 10 mg and 15 mg was less than 2 percentage points of additional weight loss, which for many people does not justify the increased side effect burden
Why muscle loss during GLP-1 therapy is a real concern The weight loss numbers from tirzepatide clinical trials are remarkable
As with any medication, potential side effects, drug interactions, and contraindications should be reviewed with a healthcare provider
While the peptide does not increase IGF-1, caution is warranted given the theoretical relationship between growth factors and cancer progression
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