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It also functions as a neurotransmitter, inhibiting the neuropeptide Y pathway, one the most potent orexigenic peptides found in the brain, while stimulating the anorexigenic pro-opiomelanocortin (POMC) pathway

However, there are a few differences to consider when comparing Tirzepatide vs Semaglutide

Searches were limited to publications in English and primarily to the last 5 years (20202024) to capture the most recent advances

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