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However, CagriSema does not include a glucagon receptor component, meaning its liver fat effects are likely mediated primarily through indirect mechanisms (weight loss, improved insulin sensitivity, reduced lipogenesis) rather than direct stimulation of hepatic fat oxidation
Although pharmacological compounds aimed at inducing ferroptosis, such as erastin and RSL3, or inhibiting it, such as ferrostatin-1 (fer-1), have demonstrated potential in preclinical studies, their application in clinical settings faces challenges, including off-target effects and limited tissue specificity [2,3,4,5,6]
Sub-Cellular Biochemistry
Common side effects
