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It mimics a natural hormone in your body called glucagon-like peptide-1 (GLP-1), which plays several important roles in managing blood sugar and appetite

Medications such as GLP-1 or GLP-1/GIP are polypeptides that have several benefits, not only with weight reduction but can also assist in helping with fatty liver disease, reducing visceral adiposity (fat surrounding internal organs), and offering cardioprotection by helping reduce high cholesterol

JAMA 286(10):12181227

A 2025 pilot study published in Headache: The Journal of Head and Face Pain found that liraglutide - a GLP-1 closely related to semaglutide - reduced average monthly migraine days from 19.8 to 10.7 in patients with chronic migraine unresponsive to at least two prior preventive treatments

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