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If additional glycemic control is needed, the dose can be increased by 2.5 mg every 4 weeks, and the maximum dose of this drug is 15 mg once a week

Secondary outcome measurements included reduction in body weight from baseline by at least 5% or 10% by week 26, changes in waist circumference, total cholesterol, HDL, LDL, VLDL, and triglycerides, and levels of different glycemic variables including HbA1C, fasting plasma glucose, fasting insulin, insulin resistance, and the functioning of beta-cells

Investigating how immune cells and their secreted factors influence the pathogenesis of osteoporosis through the regulation of bone metabolism and the inflammatory microenvironment is essential for understanding disease progression and developing novel therapeutic strategies

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The median duration of response was 13.8 months as of the data cut-off in June 2023