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In addition, presence of high concentrations of polyunsaturated fatty acids in the brain enhances their peroxidation and generation of toxic products which further causes degeneration of the cells harboring them or in vicinity 22
It contains no caffeine and produces no central nervous system activation
By reducing the overall "noise" of oxidative stress, the endocrine system can communicate more clearly, which may support more consistent hormone levels
PMID: 26371405
Contrave is generally indicated for adults with obesity or those who are overweight and have at least one weight-related comorbidity, such as high blood pressure, type 2 diabetes, or high cholesterol
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![PDF] Novel dual GLP-1/GIP receptor agonists show neuroprotective effects in Alzheimer's and Parkinson's disease models](https://figures.semanticscholar.org/d83a64f6b7193358c31030487761fc19c80dd33c/3-Figure1-1.png)
