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Retatrutide adds the cardiovascular effect of modest heart rate elevation, which is less prominent with tirzepatide and semaglutide
2016;310:R88595
The Retatrutide Dosing Schedule From Phase 2 Clinical Trials The Phase 2 trial (published in the New England Journal of Medicine) tested four retatrutide dosing schedule arms at target doses of 1mg, 4mg, 8mg, and 12mg weekly
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