Both GLP-1 medications help with weight loss and blood sugar management
Comparing Cost and Accessibility Brand-name Wegovy and Zepbound carry significant price tags, often costing $1,000 or more per month without insurance coverage
Actions of glucagon Introduction to the many actions of glucagon The physiological actions of glucagon are difficult to define due to differences between species (such as the lipolytic effects observed in rats but not in humans [68]), the rapid clearance of glucagon, dose-dependent interaction with the GLP-1 receptor [45], and direct vs indirect actions mediated by activation of the sympathetic nervous system or through secretion of hepatokines, such as fibroblast growth factor 21 (FGF21 [69])
Here is link to study: a1c reduction, weight benefits, lower side effectsonce it goes PO (for needle averse) & cost lowered (maybe?) - I see it utilized even more wondering how plans are building this inside their MLR strategy The metformin-to-GLP-1 shift in first-line prescribing is one of the fastest I have seen across any therapy class
Li Q, Yao Y, Shi S, Zhou M, Zhou Y, Wang M, Chiu JJ, Huang Z, Zhang W, Liu M