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5-azacytidine) might have a role in the treatment of breast cancer cells with epigenetically silenced CDO1for example, by inducing sensitisation to anthracycline

Unlike native IGF-1, this analog features a 13-amino acid N-terminal extension and an arginine substitution at position 3, conferring reduced affinity for insulin-like growth factor binding proteins (IGFBPs) and thus increased biological activity across multiple experimental models

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A., & Fonseca Goulart, M