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Patients learn to pace their activities, manage stress, and respond to pain in healthier ways

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This strategy suits users who achieved satisfactory improvements wanting to preserve results without full continuous intensity, willing to accept moderate benefit levels (70-85% of peak) rather than maximum continuous optimization, seeking to minimize costs while maintaining most improvements, and wanting simpler approach than complex cycling schedules

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Pharmacokinetic parameters were evaluated using the WinNonlin software (version 5.3) according to a non-atrioventricular model