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Growth Suppression Growth should be monitored during treatment with stimulants, including VYVANSE, and pediatric patients who are not growing or gaining weight as expected may need to have their treatment interrupted [see Warnings and Precautions (5.5) and Adverse Reactions (6.1)]
Elevated glutamine uptake and metabolism can contribute to TCA cycle flux and glutathione synthesis in MYCexpressing cells 12, 14, 15
Inflamm Research: Official J Eur Histamine Res Soc [et al ] 70(2):159170
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This favorable safety profile was in stark contrast to the significant toxicity (evidenced by substantial weight loss) induced by the small-molecule control agent canertinib
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