The most common include: Nausea (usually temporary and decreases over time) Gastrointestinal discomfort Constipation or diarrhea Fatigue in the initial weeks In my Miami practice, Ive found that starting with lower doses and gradually increasingalong with specific dietary recommendationssignificantly reduces these side effects
"Way back, when there really weren't too many other agents for obesity treatment," she'd prescribe more of it, she told Insider, but that was largely because "there wasn't anything else." But metformin's effects on weight loss are "kind of mild," compared to newer drugs like semaglutide, Apovian said, and persistent side effects like stomach cramps and diarrhea are a common concern among patients taking metformin
The difference isn't in strength but in how the medication enters your system and how often you take it
What are the main side effects of retatrutide seen in phase 2 studies
Keeping your body active is another important tool for staying well