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(2) molecular dynamics simulated annealing restraining FOXO4 FH (without flexible regions) harmonically to its template structure (using a non-crystallographic force constant of 10,000 kcal mol 1 2 ), with additional dihedral angle restraints from 1 H, 15 N, and 13 C chemical shifts using TALOS-N 56 , hydrogen bond restraints (region p53 residues 48-55

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Methylene blue the blue isn't dye, it's a powerful antioxidant that gives skin a more vibrant, youthful-looking finish

The dynamic phenylboronic ester hydrogel, with ROS responsiveness and scavenging capabilities, helps alleviate inflammation and serves as a drug reservoir for the controlled release of D-CuP at the wound site

It demonstrates potent anti-glioblastoma activity by: (1) blocking tumor invasion and cytokinesis (inducing polyploidy), (2) disrupting mitochondrial dynamics to elevate ROS and trigger ferroptosis, and (3) sensitizing tumors to radiotherapy/kinase inhibitors via ROS-driven PDGFR/mTOR pathway activation