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You may be able to work around these problems, but a simpler alternative is a sturdy Nalgene Bottle

The first is a hidden pocket above the shoulder straps against the back panel, which is large enough to hold multiple flat items such as a cell phone, passport, and wallet

This is an excellent option for international business travellers

However, doing so certainly pushes the four-pound base weight closer to 15 or 20 pounds in a hurry, which is certainly something to consider

To isolate the most improved variants, we increased the selection stringency by reducing IPTG (20 M) and CML (100 M) concentrations and only selecting colonies that appeared within two days