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Generic Adempas : Rioteph 0.5 mg (Riociguat) Generic Adempas : Rioteph 0.5 mg (Riociguat):90 Tablet/s Q2: How should I takeBuy Rioteph 0. 5 mg (Riociguat) Generic Adempas for PAH & CTEPH Rioteph 0. 5 mg contains riociguat, a soluble guanylate cyclase stimulator used to treat adults with pulmonary arterial hypertension (PAH, WHO Group 1) and chronic thromboembolic pulmonary hypertension (CTEPH) when surgery isn't an option or symptoms persist post surgery. How It Works Riociguat enhances the enzyme soluble guanylate cyclase, increasing cyclic GMP in vascular smooth muscle