Recombinant Human Dickkopf-related protein-1,His (Human DKK-1,His )_C230321 Other Proteins TAFAs may modulate immune responses

TAFAs may modulate immune responses in the CNS by functioning as brain-specific chemokines

Accumulated experimental evidence supports that

1 ((Met1-Arg192)

GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK

It contains Ser19-Asn178

Recombinant Human Dickkopf-related protein-1,His (Human DKK-1,His )_C230321 Other Proteins TAFAs may modulate immune responsesDickkopf related protein 1 (Dkk 1) is the founding member of the Dickkopf family of proteins that includes Dkk 1, 2, 3, 4, and a related protein, Soggy. Dkk proteins are secreted proteins that contain two conserved cysteine rich domains separated by a linker region. Each domain contains ten cysteine residues . Mature human Dkk 1 is a 40 kDa glycosylated protein that shares 86%, 87%, 90% and 91% aa sequence identity with mouse, rat, rabbit and bovine