Recombinant Human PDGF-BB Protein _ C230478 Size:100 μg the product of the FABP3

the product of the FABP3 gene

this protein has variously been referred to as heparin-binding brain mitogen (HBBM)

IGF-1 promote the proliferation of multiple myeloma (MM) cells and protect them against dexamethasone (Dex)-induced apoptosis

The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 0

The biological activity determined by a chemotaxis bioassay using PHA and rHuIL-2 activated human peripheral blood T-lymphocytes is in a concentration range of 20-80 ng/mL

Recombinant Human PDGF-BB Protein _ C230478 Size:100 μg the product of the FABP3Platelet derived growth factor (PDGF) was discovered as a major mitogenic factor present in serum but absent from plasma. In vitro, PDGF BB stimulated MAP kinase activity and cell motility of isolated lymphatic endothelial cells. In vivo, PDGF BB potently induced growth of lymphatic vessels. Expression of PDGF BB in murine fibrosarcoma cells induced tumor lymphangiogenesis, leading to enhanced metastasis in lymph nodes. The PDGF signaling system