Recombinant Human Insulin-like Growth Factor-Binding Protein 3 (Human IGF-BP3)_C230373 Other growth factors and exhibits considerable species crossreactivity

and exhibits considerable species crossreactivity

and a 30 aa cytoplasmic tail

vascular endothelial growth factor D

Mature human VEGF-D shares 94%

6 kDa monomeric protein

Recombinant Human Insulin-like Growth Factor-Binding Protein 3 (Human IGF-BP3)_C230373 Other growth factors and exhibits considerable species crossreactivityIGF BP3 is a 30 kDa, cysteine rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals, and it is also found in granules of platelets. In addition to its ability to modulate the activity of IGF I and IGF II, IGF BP3 exerts inhibitory effects on follicle stimulating hormone (FSH) activity. Decreased plasma levels of IGF BP3 often results in dwarfism, whereas elevated levels of IGF BP3 may lead to acromegaly.