Recombinant Human Stromal-Cell Derived Factor-1 gamma/CXCL12 gamma (Human SDF-1γ/CXCL12γ)_C230499 Other Proteins and polyploidization in megakaryocytes

and polyploidization in megakaryocytes

Gly64-Asp24

Interleukin-12

Ala20-Phe152

This activation leads to downstream signaling events that impact cell behavior and tissue development

Recombinant Human Stromal-Cell Derived Factor-1 gamma/CXCL12 gamma (Human SDF-1γ/CXCL12γ)_C230499 Other Proteins and polyploidization in megakaryocytesHuman CXCL12 is expressed as five isoforms that differ only in the C terminal tail. The gamma isoform of CXCL12, also known as SDF 1 gamma, is a 12 kDa, heparin binding member of the CXC (or alpha) family of chemokines ,Mature SDF 1 molecules are not glycosylated and exhibit a typical three antiparallel beta strand chemokine like fold. N terminal aa 1 8 form a receptor binding site, while aa 1 and 2 (Lys Pro) are involved in receptor activation. All