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Removal of the first 5 aa of the mature protein
Leucine-rich repeat-containing G-protein coupled receptor 6
this 8-9 kDa chemokine contains an ELR motif which is important for its angiogenic properties
without affecting IGF-induced proliferation
2 µm filtered solution in 20 mM PB
Recombinant Human Epiregulin (Human Epiregulin)_C230332 Size:500 μg Removal of the first 5Epiregulin is an EGF related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor derived epithelial cell lines.
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