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Amplification Protocol
triggering IL-6 R alpha association with gp130 and gp130 dimerization
Thr23-Thr125
The mature protein forms a disulfide-linked head-to-tail homodimer of 16 kDa
The protein has a predicted MW of 23
Recombinant Human Otoraplin (Human OTOR) _ C230469 Cell culture medium Amplification ProtocolOTOR also named Otoraplin and MIAL, is a 15 kDa disulfide bonded homodimer, which is secreted via the Golgi apparatus and is a member of the MIA OTOR family. The OTOR shares high sequence identity with the mouse (90%), chicken (80%), and bullfrog (60%) orthologs and with the related human CDRAP MIA protein (43%). Members of this family which also includes MIA, MIA2, and TANGO share a Src homology 3 (SH3) like domain. OTOR is mainly expressed in the
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