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Activating pathways for creation of NADPH has been shown to protect RPE cells from oxidative damage 74 , and our findings indicate that for developing mouse retinas with RP in which all rods have been lost a possible intervention strategy would be to stimulate synthesis of NADPH

The authors carefully adhered to the lifestyle interventions mandated by the FDA and its European counterpart for clinical trials of medications for type 2 diabetes and obesity in the pediatric age range [18,19]