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Typical therapeutic doses can range from 1000 mcg once weekly to monthly

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Patients who have a history of stimulant use but are no longer on ADHD medication frequently require higher doses to achieve meaningful appetite suppression, and even then outcomes can be more limited

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Whilst some studies found beneficial effects in patients with AD 36 and dementia 90 and in shift workers, 91 others found no improvements in patients with sleepwake rhythm disorders