semaglutide oral side effects dehydration Ozempic (Semaglutide): GLP-1 receptor agonist used for type 2 diabetes. It commonly causes dose-related gastrointestinal side- effects, while important serious warnings include pancreatitis, gallbladder disease, dehydration Everything You Need To Know

Wegovy became approved for weight loss in 2021

HbA1c reductions up to 1.6 percentage points Weight trajectory: Weight loss had not plateaued by 52 weeks, indicating potential for further reduction with continued treatment Cardiometabolic: Improvements in waist circumference, blood pressure, hs-CRP, and lipid parameters Evidence level: Moderate -- well-designed phase 2 with NEJM publication, but single trial, no head-to-head comparisons

10.1038/s41467-017-01778-9 76 ZhouH.Mayorga-MartinezC

This can lead to improved health and lower the risk of conditions like heart disease and high blood pressure

Applied & Environmental Microbiology, 69: 74927498