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Identification and selective inhibition of an isozyme of steroid 5a-reductase in human scalp.Proc

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Since mitochondrial problems begin to occur early and because they are shared among species, we first investigated potential changes in metabolite dynamics, especially in the motor cortex of prpTDP-43 A315T mice, which closely recapitulates ALS pathology in patients 16,17,19

Among the seleno-GPxs, GPx2 and GPx4 have the highest priority for selenium utilization, suggesting the important roles played by them in maintaining the cellular antioxidant defense mechanisms [8, 25]

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