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A large 24-week trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo when combined with diet and exercise
In contrast, in the obese ob/ob mice, both AOD9604 and hGH caused a pronounced decrease in body weight
A more individualized response-based approach monitors body composition changes and continues therapy as long as positive progress occurs, adjusting or pausing when plateaus develop or goals are achieved
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