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There is excitement among addiction researchers around the idea that designing GLP-1 agonists with higher blood-brain barrier penetration and more selective central nervous system targets can be a next frontier in addiction treatment

The medication works by activating GLP-1 receptors in the brain to reduce hunger signals and increase feelings of fullness

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Semaglutide is a GLP-1 receptor agonist that targets appetite regulation, glucose metabolism and cardiovascular risk

doi: 10.3892/mmr.2016.4807 201 BogavacMJakovljeviANikoliAMiloevi ToiMPeriTBelopavloviZ