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It downregulates Bax/caspase-3 and upregulates Bcl-2 to inhibit apoptosis (Li et al., 2024), and activates the PI3K/AKT/GSK3 pathway to reduce apoptosis, improve contractile function, and alleviate PD1-induced myocardial fibrosis and necrosis (Huang et al., 2025)
Int J Obes Relat Metab Disord 23:723732 Baggio LL, Drucker DJ (2007) Biology of incretins: GLP-1 and GIP
-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming
Stable gastric pentadecapeptide BPC 157 heals rat colon anastomotic leakage
Additionally, they must be used under the supervision of a healthcare professional to ensure they are tailored to individual needs and to minimize risks
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