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39, 40, 41, 42 Four independent casecontrol studies from our group have documented glutathione deficits in plasma, immune cells and post-mortem brain from ASD children, 6, 43, 44, 45 but other groups have also verified glutathione abnormalities in post-mortem brain, 46 demonstrated ROS-mediated damage to mtDNA 47 and lipids, 48 identified abnormalities in other ROS biomarkers such as homocysteine 49 as well as found epigenetic changes potentially related to redox abnormalities
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In it, a group of 25 patients with diabetes were treated with 600mg of silymarin per day, divided into three doses
Weight reduction achieved through these agents facilitates management of other diabetes co-morbidities and reduces cardiovascular complications
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