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The escalation window allows time to assess whether mild nausea, appetite suppression, or energy changes represent temporary adaptation or signal a need to slow progression
This strategy is the basis for many anticancer therapeutics, including chemotherapeutics, radiotherapies, and most small-molecule inhibitor-based therapies, which impair tumor metabolism and induce excessive ROS accumulation, inducing cell toxicity and death
J Int Soc Sports Nutr 15:10 Yasuda J, Tomita T, Arimitsu T, Fujita S (2020) Evenly distributed protein intake over 3 meals augments resistance Exercise-Induced muscle hypertrophy in healthy young men
doi:10.1105/tpc.107.052597