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Under normal physiological conditions, activation of the Keap1-NRF2 signaling pathway promotes the activation of System Xc - and the expression of GPX4 and accelerates cysteine glutamate transport, thereby clearing accumulated lipid peroxidation and inhibiting ferroptosis (86)

The SMA voxel was placed symmetrically over the midline with its posterior face anterior to the central sulci(Boy et al., 2010)

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