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Can occur with Synjardy: lactic acidosis (increased acid level in your blood) Can occur with Jardiance: no unique serious side effects Can occur with both Synjardy and Jardiance: severe allergic reaction Fourniers gangrene (severe infection near your genitals) hypoglycemia (low blood sugar level) increased low-density lipoprotein (LDL) cholesterol level ketoacidosis (a buildup of ketones in your body, which causes your blood to become too acidic) low level of fluid in the body serious UTIs, including pyelonephritis (infection that affects your kidneys) and urosepsis (infection that affects your bloodstream) Effectiveness The use of Synjardy and Jardiance in treating type 2 diabetes has been directly compared in a clinical study

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