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[8] : 322 One often-stated rule of thumb is that melena only occurs if the source of bleeding is above the ligament of Treitz although, as noted below, exceptions occur with enough frequency to render it unreliable

And in August, Pfizer ended development of its third and final oral GLP-1 candidate, PF-06954522, after a review of its phase 1 clinical performance and the overall GLP-1 landscape