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This gentle approach preserves the peptides structural integrity
So, the B12 in the serum is OK, but in the brain, it is low
For this reason, patients with Parkinsons disease on levodopa therapy should avoid high B intake unless they are also taking carbidopa (which prevents this interaction)
Most patients notice improvements within 2-4 weeks, but if youre not seeing changes, we pivot the approach until we find what works
If it has not, I think harder about dose, about the route of administration (oral versus intramuscular), and about other possible contributors
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