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Blockbuster weight-loss drugs are revealing how appetite, pleasure and addiction work in the brain Lauren J
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Doseresponse effects on HbA1c and bodyweight reduction of survodutide, a dual glucagon/GLP-1 receptor agonist, compared with placebo and open-label semaglutide in people with type 2 diabetes: a randomised clinical trial
The trial was funded by Eli Lilly and Company, the manufacturer of Mounjaro and Zepbound
injections of 100 nmol kg 1 MK-801 ( n = 8 mice), 100 nmol kg 1 GLP-1 ( n = 8 mice), 100 nmol kg 1 GLP-1MK-801 (Cys-linked) ( n = 8 mice) or vehicle (isotonic saline, n = 8 mice) for 5 days
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