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Side effects are rare and typically limited to mild injection-site tenderness

Procaine is well-recognised for its analgesic properties and ability to alleviate pain

Rosenstock J, Frias J, Jastreboff AM, et al

It has been used: As part of the treatment for cyanide poisoning To dye tissues during surgery to determine tumors To relieve pain caused by oral mucositis To identify orthopedic injury to joint capsules To treat malaria before modern treatments were developed To treat encephalopathy, or confusion caused by chemotherapy Exploring other uses for methylene blue Earlier in my career, while working in emergency medicine, I read two papers that discussed using methylene blue as part of photodynamic therapy for lichen planus, a type of precancerous lesion in the mouth