Leptin is a trigger for an inflammatory response in skin, so this is perhaps why obesity can trigger more severe psoriasis flares. A separate study last year (6) found that psoriasis patients who were taking glucagon-like peptide-1 receptor agonists for type 2 diabetes showed a significant reduction in PASI scores, which are a measuring scale for the severity of psoriasis, with fewer markers for of inflammation in layers of the skin and reduced auto immune responses
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These can include: Gastrointestinal discomfort Bloating or gas Allergic reactions in some cases As with any supplement, it's essential to monitor how your body responds and adjust your intake accordingly
Yenin JZ, Serarslan G, Yonden Z, Uluta KT
(b) Pitavastatin decreased the mRNA expressions of gp91 phox , p47 phox , and p67 phox , all of which are related to oxidative stress