Given our findings, future research with Dandelion data will focus on (i) investigating the heterogeneity in treatment response to GLP-1s, (ii) modeling predictors of patient responsiveness, and (iii) analyzing unstructured clinical data to understand the impact of GLP-1s on measures beyond weight loss and HbA1c (e.g., loss or preservation of lean body mass)
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The ATTAIN global phase 3 registration program demonstrated clinically significant and meaningful body weight reduction along with improvements in markers of cardiometabolic disease, such as waist circumference, blood pressure, lipids and highsensitivity Creactive protein, in people with obesity, with and without type 2 diabetes, with an efficacy and safety profile generally similar to injectable incretin-based OMMs 3,9
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